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Pedro Filho Noronha Souza

Universidade Federal do Ceará · CE · 83 publicações em 2022–2026

ORCID 0000-0003-2524-4434

Antimicrobial Peptides and ActivitiesAntifungal resistance and susceptibilityAntimicrobial agents and applicationsSARS-CoV-2 and COVID-19 ResearchComputational Drug Discovery Methods

Principais coautores no Nordeste tamanho = publicações em comum

Felipe Pantoja Mesquita Raquel Carvalho Montenegro Cléverson D.T. Freitas Emerson Lucena da Silva Maria Elisabete Amaral de Moraes Nilton A. S. Neto Daiane Maria da Silva Brito Débora de Souza Collares Maia Castelo‐Branco Tawanny K. B. Aguiar Luciana Magalhães Rebêlo Alencar Laís Lacerda Brasil de Oliveira Ayrles F.B. Silva

Publicações recentes

2026 9

Mebendazole impairs the expression and function of enzymes in nucleotide metabolism pathways, leading to Selective Cytotoxicity, Cell Cycle Arrest, and Damage to Cell Morphology in Gastric Cancer
Bioquímica, genética e biologia molecular · Chemico-Biological Interactions
Regulatory landscape for CAR-T therapy development in the Brazilian context
Medicina · Expert Review of Anticancer Therapy
Antifungal activity of emodin against the Cryptococcus neoformans / Cryptococcus gattii complexes: an effect on the enzyme superoxide dismutase
Medicina · Canadian Journal of Microbiology
Mo-CBP3-PepIII Changes the Proteomic Profile of Gastric Cancer Cells, Induces Membrane Pore Formation, and ROS Overaccumulation
Imunologia e microbiologia · International Journal of Peptide Research and Therapeutics
RcAlb-PepII Perturbs the Proteomic Profile of Cryptococcus neoformans, Shutting Down Proteins Involved in Fungal Survival
Imunologia e microbiologia · Microorganisms
Correction to: Evaluation in vitro and in silico of LIG08, a benzoxathiolone-thiazolidinone derivative, as a potential drug against Klebsiella pneumoniae
Farmacologia e toxicologia · Biologia
DAL, lectin from Dioclea altissima: Three-dimensional structure resolution by X-ray diffraction and in silico prospection for targeting Mpro from SARS-CoV-2
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
Unraveling the mechanism of action of the PepGAT peptide against Candida albicans through proteomics approaches
Imunologia e microbiologia · Scientific Reports
LASSBio-1986 as a Multifunctional Antidiabetic Lead: SGLT1/2 Docking, Redox–Inflammatory Modulation and Metabolic Benefits in C57BL/6 Mice
Medicina · International Journal of Molecular Sciences

2025 15

Agrochemical fungicides as environmental drivers of antifungal resistance
Medicina · The Science of The Total Environment
Antimicrobial and antiparasitic potential of lupeol: antifungal effect on the Candida parapsilosis species complex and nematicidal activity against Caenorhabditis elegans
Medicina · Journal of Medical Microbiology
Pandemic Events Caused by Bacteria Throughout Human History and the Risks of Antimicrobial Resistance Today
Medicina · Microorganisms
Effect of 5-fluorouracil on Escherichia coli and Enterococcus spp.: insights into the selective pressures caused by this cytotoxic drug
Bioquímica, genética e biologia molecular · Microbial Pathogenesis
Unleashing the power of the BCG vaccine in modulating viral immunity through heterologous protection: A scoping review
Imunologia e microbiologia · Human Vaccines & Immunotherapeutics
Structural and biochemical characterization of a thermostable Bacillus subtilis L-asparaginase with antiproliferative effects on hematological cancer cell lines
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
Proteins from Kappaphycus alvarezii: Identification by Mass Spectrometry and Antifungal Potential
Ciências agrárias e biológicas · Processes
Proteomic Analysis Revealed that DVL, a Lectin Purified from Dioclea violacea Seeds, Induced a Change in the Protein Profile of Candida albicans
Medicina · ACS Omega
PepGAT, a chitinase-derived peptide, alters the proteomic profile of colorectal cancer cells and perturbs pathways involved in cancer survival
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
DVL, a Lectin from Dioclea violacea Seeds, Disturbs the Proteomic Profile of Candida krusei, Leading to Cell Death
Medicina · Antibiotics
FLA94, an isatin derivative, inhibits Candida albicans growth by inducing membrane damage and ROS overaccumulation
Medicina · Future Microbiology
Development of a Peptide-Based Multiepitope Vaccine from the SARS-CoV-2 Spike Protein for Targeted Immune Response Against COVID-19
Bioquímica, genética e biologia molecular · Protein and Peptide Letters
Melanoma Spotlight: New Perspectives Through Biophysical Markers
Bioquímica, genética e biologia molecular · Cell Biochemistry and Biophysics
Aurein 1.2 analogues as promising agents against Candida parapsilosis : insights into mechanism and biofilm disruption
Imunologia e microbiologia · Future Microbiology
Associations Between APOE Polymorphisms, Neurological Symptoms, and Cognitive Assessments in Long COVID Patients: An Analysis of SNPs rs7412 and rs429358
Medicina · Molecular Neurobiology

2024 16

Antifungal activity of Caryocar brasiliense camb. Alone or along with antifungal agents against multidrug-resistant Candida auris
Medicina · Journal of Ethnopharmacology
Synthetic Peptides Induce Human Colorectal Cancer Cell Death via Proapoptotic Pathways
Imunologia e microbiologia · ACS Omega
Rise and fall of Caspofungin: the current status of Caspofungin as a treatment for Cryptococcus neoformans infection
Medicina · Future Microbiology
Molecular characterization and biomarker discovery in gastric cancer progression through transcriptome meta-analysis
Medicina · Computers in Biology and Medicine
Tofacitinib and peficitinib inhibitors of Janus kinase for autoimmune disease treatment: a quantum biochemistry approach
Farmacologia e toxicologia · Physical Chemistry Chemical Physics
Human TMPRSS2 and ACE2 genetic variability on COVID-19 outcomes in patients from Brazil
Medicina · Human Gene
Transcriptome analysis displays new molecular insights into the mechanisms of action of Mebendazole in gastric cancer cells
Medicina · Computers in Biology and Medicine
A Review on Anaplastic Lymphoma Kinase (ALK) Rearrangements and Mutations: Implications for Gastric Carcinogenesis and Target Therapy
Medicina · Current Protein and Peptide Science
Chia nanoemulsion: anti-inflammatory mechanism, biological behavior and cellular interactions
Enfermagem · Therapeutic Delivery
Synthetic antimicrobial peptides: activity against vancomycin-resistant Enterococcus faecalis and modulation of chloramphenicol antibacterial activity
Imunologia e microbiologia · Journal of Applied Microbiology
Influence of carbonyl cyanide m-chlorophenyl hydrazone on biofilm dynamics, protease, and siderophore production by Burkholderia pseudomallei
Bioquímica, genética e biologia molecular · Biofouling
In silico approach revealed the membrane receptor PHO36 as a new target for synthetic anticandidal peptides
Imunologia e microbiologia · Future Microbiology
Antibodies as Promising Molecules to Block Spike Glycoprotein from SARS-CoV-2
Medicina · Coronaviruses
Medical Records Data and In silico Analysis Provide New Insights About COVID-19 in Smokers
Medicina · Coronaviruses
Common sense: why bacterial sensing systems are an important target for new antibiotics
Bioquímica, genética e biologia molecular · Future Microbiology
The Polypeptides/Proteins Exuded from Mimosa caesalpiniifolia Seeds Induce Ultrastructural and Biomechanical Modifications of the Caenorhabditis elegans Surface and Inhibit the Nematode Motility.
Imunologia e microbiologia · Brazilian Archives of Biology and Technology

2023 10

A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi
Medicina · Nature Communications
Antioxidant peptides from plants: a review
Ciências agrárias e biológicas · Phytochemistry Reviews
Mebendazole targets essential proteins in glucose metabolism leading gastric cancer cells to death
Bioquímica, genética e biologia molecular · Toxicology and Applied Pharmacology
A historical, economic, and technical-scientific approach to the current crisis in the development of antibacterial drugs: Promising role of antibacterial peptides in this scenario
Imunologia e microbiologia · Microbial Pathogenesis
DVL, lectin from Dioclea violacea seeds, has multiples mechanisms of action against Candida spp via carbohydrate recognition domain
Medicina · Chemico-Biological Interactions
Antimicrobial Activity the Essential Oil from Croton pluriglandulosus Carn. Leaves against Microorganisms of Clinical Interest
Ciências agrárias e biológicas · Journal of Fungi
Proteomic analysis of Cryptostegia grandiflora latex, purification, characterization, and biological activity of two osmotin isoforms
Imunologia e microbiologia · International Journal of Biological Macromolecules
Behind the Curtain: In Silico and In Vitro Experiments Brought to Light New Insights into the Anticryptococcal Action of Synthetic Peptides
Imunologia e microbiologia · Antibiotics
No Chance to Survive: Mo-CBP3-PepII Synthetic Peptide Acts on Cryptococcus neoformans by Multiple Mechanisms of Action
Medicina · Antibiotics
A Shortcut from Genome to Drug: The Employment of Bioinformatic Tools to Find New Targets for Gastric Cancer Treatment
Farmacologia e toxicologia · Pharmaceutics

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