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Maria do Carmo Alves de Lima

Universidade Federal de Pernambuco · PE · 38 publicações em 2022–2026

ORCID 0000-0002-8277-3458

Heterocyclic Compound Synthesis and BioactivitySynthesis and Characterization of Heterocyclic CompoundsParasites and Host InteractionsPeroxisome Proliferator-Activated ReceptorsCancer therapeutics and mechanisms

Principais coautores no Nordeste tamanho = publicações em comum

Iranildo José da Cruz Filho Diego Santa Clara Marques Luiz Carlos Alves Jamerson Ferreira de Oliveira André de Lima Aires Fábio André Brayner Maria Emanuelle de Oliveira Queirós Íris Trindade Tenório Jacob Lisandra da Silva Lima Sinara Mônica Vitalino de Almeida Arthur Van Lauter Albuquerque Pereira Fábio André Brayner dos Santos

Publicações recentes

2026 6

Thiazole as a Promising Scaffold for the Treatment of Schistosomiasis: In Vitro and In Vivo Activity Against Different Developmental Stages of Schistosoma mansoni
Imunologia e microbiologia · Pharmaceuticals
Casca do café como recurso sustentável: composição química, bioatividade e aplicações na economia circular
Medicina · Scientific Electronic Archives
Indole–thiazole derivatives as schistosomicidal agents against Schistosoma mansoni: synthesis, in vitro and in vivo efficacy, immunomodulation, and in silico interaction with cathepsin B1
Imunologia e microbiologia · Bioorganic Chemistry
Antiproliferative Activity, DNA/HSA Interactions and Human Topoisomerase Inhibition Evaluations of Indole-Thiazolidinone Derivatives: Are Two Indole Rings Better than One?
Bioquímica, genética e biologia molecular · Current Topics in Medicinal Chemistry
Preliminary evaluation of the in vitro biological activities of crude wood extracts of Dinizia excelsa Ducke obtained using methanolic, aqueous, acetonitrile, dichloromethane, chloroform, and hexane solvents
Ciências agrárias e biológicas · Anais da Academia Brasileira de Ciências
Ethyl acetate extract from Dinizia excelsa Ducke wood: A potential phytotherapeutic agent with antioxidant, cytotoxic and hemolytic (in normal cells), immunomodulatory, antimicrobial, antiparasitic and antitumor activities
Ciências agrárias e biológicas · Molecular and Biochemical Parasitology

2025 6

In Vitro and Ultrastructural Evaluation of the Cytotoxic and Antileishmanial Activities of Thiosemicarbazone Compounds Against Promastigotes and Axenic Amastigotes of Leishmania infantum
Medicina · Tropical Medicine and Infectious Disease
Evaluation of the Biological Activities of Dinizia excelsa Wood Essential Oil: A Potential Phytotherapeutic Agent
Ciências agrárias e biológicas · Chemistry & Biodiversity
Essential Oil From the Wood of Clarissa racemosa : Chemical Characterization, In Vitro Evaluation of Biological Activities, a Promising Phytopharmaceutical
Ciências agrárias e biológicas · Chemistry & Biodiversity
Perfil microbiológico de pacientes com infecção do trato urinário internados em UTI covid de um hospital de referência
Medicina · Revista Brasileira Multidisciplinar
Bis-MPA polymer inclusion complex/thiophene-acridine derivative: Antiparasitic and immunomodulatory potential against Leishmania infantum, Leishmania amazonensis and Schistosoma mansoni
Medicina · Journal of Drug Delivery Science and Technology
Preliminary Evaluation of HSA and DNA Interactions with Indole-Thiosemicarbazone Compounds and Molecular Docking Studies
Bioquímica, genética e biologia molecular · Brazilian Archives of Biology and Technology

2024 7

Therapeutic potential of hydantoin and thiohydantoin compounds against Schistosoma mansoni: An integrated in vitro, DNA, ultrastructural, and ADMET in silico approach
Imunologia e microbiologia · Molecular and Biochemical Parasitology
Xylans as a promising prebiotic agent: a brief review
Enfermagem · Scientific Electronic Archives
The Imidazacridine Derivative LPSF/AC-05 Induces Apoptosis, Cell Cycle Arrest, and Topoisomerase II Inhibition in Breast Cancer, Leukemia, and Lymphoma
Bioquímica, genética e biologia molecular · Current Cancer Drug Targets
Xylan from Dinizia excelsa: Chemical characterization and biological activities
Ciências agrárias e biológicas · Anais da Academia Brasileira de Ciências
5-nitro-thiophene-thiosemicarbazone derivative induces cell death, cell cycle arrest, and phospho-kinase shutdown in pancreatic ductal adenocarcinoma cells
Medicina · European Journal of Pharmacology
A utilização de plantas medicinais como terapia complementar no manejo do diabetes mellitus e suas complicações
Medicina · Revista Eletrônica Acervo Saúde
Spectroscopic exploration of mode of binding of ct DNA and BSA with acridone alkaloids isolated from Zanthoxylum leprieurii (Rutaceae)
Bioquímica, genética e biologia molecular · Natural Product Research

2023 14

Synthesis of 4-(4-chlorophenyl)thiazole compounds: in silico and in vitro evaluations as leishmanicidal and trypanocidal agents
Medicina · Anais da Academia Brasileira de Ciências
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation
Medicina · Pharmaceuticals
Interaction study with DNA/HSA, anti-topoisomerase IIα, cytotoxicity and in vitro antiproliferative evaluations and molecular docking of indole-thiosemicarbazone compounds
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
In silico ADMET prediction, evaluation of cytotoxicity in mouse splenocytes and preliminary evaluation of in vitro antimalarial activity of 4-(4-chlorophenyl)thiazole compounds
Medicina · Anais da Academia Brasileira de Ciências
Alkaline lignins from Morinda citrifolia leaves are potential immunomodulatory, antitumor, and antimicrobial agents
Medicina · Anais da Academia Brasileira de Ciências
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
In vitro activity, ultrastructural analysis and in silico pharmacokinetic properties (ADMET) of thiazole compounds against adult worms of Schistosoma mansoni
Imunologia e microbiologia · Acta Tropica
Xylans extracted from branches and leaves of Protium puncticulatum: antioxidant, cytotoxic, immunomodulatory, anticoagulant, antitumor, prebiotic activities and their structural characterization
Ciências agrárias e biológicas · 3 Biotech
Development and evaluation of the in vitro schistosomicidal activity of solid dispersions based on 2-(-5-bromo-1-H-indole-3-yl-methylene)-N-(naphthalene-1-ylhydrazine-carbothiamide
Farmacologia e toxicologia · Experimental Parasitology
Development of solid dispersions based on 3- (2,6-difluorobenzyl) -5- (5-bromo-1H-indol-3-ylmethylene) thiazolidine-2,4-dione for schistosomicidal treatment
Farmacologia e toxicologia · Experimental Parasitology
Evaluation of the hydroalcoholic extract of Clarisia racemosa as an antiparasitic agent: an in vitro approach
Ciências agrárias e biológicas · 3 Biotech
Pectin-like polysaccharide extracted from leaves Crataeva tapia promotes antioxidant, immunomodulatory and emulsifiers applied in therapeutic formulations
Ciências agrárias e biológicas · 3 Biotech
Development of inclusion complex based on cyclodextrin and oxazolidine derivative
Farmacologia e toxicologia · Brazilian Journal of Pharmaceutical Sciences
Pre-formulation study and evaluation of antifungal activity for Clarisia racemosa sporotrichosis
Ciências agrárias e biológicas · Concilium

2022 5

Photoprotective, biological activities and chemical composition of the non-toxic hydroalcoholic extract of Clarisia racemosa with cosmetic and pharmaceutical applications
Ciências agrárias e biológicas · Industrial Crops and Products
Synthesis, in Vitro Schistosomicidal Activity and Ultrastructural Alterations Caused by Thiosemicarbazones and Thiazolidinones Against Juvenile and Adult Schistosoma Mansoni Worms (Sambon, 1907)
Imunologia e microbiologia · Molecular and Biochemical Parasitology
Thiazolidine derivatives: In vitro toxicity assessment against promastigote and amastigote forms of Leishmania infantum and ultrastructural study
Medicina · Experimental Parasitology
Neurolocomotor Behavior and Oxidative Stress Markers of Thiazole and Thiazolidinedione Derivatives against Nauphoeta cinerea
Ciências agrárias e biológicas · Antioxidants
Pectin-like Polysaccharide Extracted from the Leaves Caesalpinia pulcherrima is a Promising Antioxidant and Immunomodulator Agent
Ciências agrárias e biológicas · Brazilian Archives of Biology and Technology

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