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Ricardo Olímpio de Moura

Universidade Estadual da Paraíba · PB · 44 publicações em 2022–2026

ORCID 0000-0002-1590-3750

Heterocyclic Compound Synthesis and BioactivityComputational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic CompoundsCancer therapeutics and mechanismsResearch on Leishmaniasis Studies

Principais coautores no Nordeste tamanho = publicações em comum

Igor José dos Santos Nascimento Sonaly Lima Albino Karla Joane da Silva Menezes Misael de Azevedo Teotônio Cavalcanti Yvnni Maria Sales de Medeiros e Silva Jéssika de Oliveira Viana Malu Maria Lucas dos Reis Sinara Mônica Vitalino de Almeida Vanda Lúcia dos Santos Euzébio Guimarães Barbosa Gleyton Leonel Silva Sousa Jamire Muriel da Silva

Publicações recentes

2026 8

Bioinformatics in Antifungal Design: Strategies To Overcome Resistance from a Proteomic Perspective
Medicina · Current Fungal Infection Reports
Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy
Bioquímica, genética e biologia molecular · Pharmaceuticals
Ensemble Docking, MD, and MM/PBSA Identify Flavonoids as Putative Modulators of EFNB2/B3-Nipah Virus G Interaction
Farmacologia e toxicologia · International Journal of Molecular Sciences
Design, Synthesis, and Antimalarial Evaluation of Novel Quinazolin-4(3 H )-one Derivatives with Molecular Modeling Insights into Target Selectivity
Medicina · ACS Omega
Indole–thiazole derivatives as schistosomicidal agents against Schistosoma mansoni: synthesis, in vitro and in vivo efficacy, immunomodulation, and in silico interaction with cathepsin B1
Imunologia e microbiologia · Bioorganic Chemistry
Computational Identification of Potential Novel Allosteric IHF Inhibitors Using QSAR Modeling to Inhibit Plasmid-Mediated Antibiotic Resistance
Farmacologia e toxicologia · International Journal of Molecular Sciences
Development and Characterization of Liposomes Containing a Zn(II) Porphyrin Derivative for the Application of Photodynamic Therapy in the Treatment of Breast Cancer
Bioquímica, genética e biologia molecular · Lasers in Surgery and Medicine
Latest developments in small molecule inhibitors of cysteine protease B as antileishmanial drugs
Medicina · Future Medicinal Chemistry

2025 11

Targeting cysteine protease B to discover antileishmanial drugs: Directions and advances
Medicina · European Journal of Medicinal Chemistry
Synthesis, Biological Evaluation, Molecular Dynamics, and QM-MM Calculation of Spiro-Acridine Derivatives Against Leishmaniasis
Medicina · Microorganisms
Laponite®-Based Smart Hydrogels for Sustained Topical Delivery of Silver Sulfadiazine: A Strategy for the Treatment of Contaminated or Biofilm-Forming Wounds
Medicina · Pharmaceutics
N-acyl hydrazone derivatives reduce pro-inflammatory cytokines, iNOS and COX-2 in acute lung inflammation model
Medicina · Chemico-Biological Interactions
Target Selectivity of Cysteine Protease Inhibitors: A Strategy to Address Neglected Tropical Diseases
Medicina · Current Medicinal Chemistry
Exploring Subtilisin Inhibition to Discover Antimalarial Drugs: Insights into Medicinal Chemistry and Drug Discovery
Medicina · Pharmaceuticals
N-Myristoyltransferase Inhibition in Parasitic Pathogens: Insights from Computer-Aided Drug Design
Farmacologia e toxicologia · Molecules
Design, Synthesis, and Antimalarial Evaluation of New Spiroacridine Derivatives
Medicina · Antibiotics
Análise in silico de moléculas sintéticas de hidrazina-1-carbotioamidas
Farmacologia e toxicologia · BIOFARM - Journal of Biology & Pharmacy and Agricultural Management
Nanostructured lipid carriers containing pheophytins derived from Cnidoscolus quercifolius Pohl for photodynamic therapy against breast cancer: isolation, identification, characterization, in vitro activity, and in silico studies
Bioquímica, genética e biologia molecular · Lasers in Medical Science
Potencial antiangiogênico do derivado 9-aminoacridínico ACS-AZ-10:
Farmacologia e toxicologia · BIOFARM - Journal of Biology & Pharmacy and Agricultural Management

2024 9

Molecular Dynamics Simulations in Drug Discovery
Farmacologia e toxicologia · Mini-Reviews in Medicinal Chemistry
Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors
Bioquímica, genética e biologia molecular · Results in Chemistry
Anticancer Drug Discovery from Natural Compounds Targeting PI3K/AKT/mTOR Signaling Pathway
Bioquímica, genética e biologia molecular · Current Medicinal Chemistry
Discovery of novel thiosemicarbazone-acridine targeting butyrylcholinesterase with antioxidant, metal complexing and neuroprotector abilities as potential treatment of Alzheimer's disease: In vitro, in vivo, and in silico studies
Medicina · European Journal of Medicinal Chemistry
Insights to Design New Drugs against Human African Trypanosomiasis Targeting Rhodesain using Covalent Docking, Molecular Dynamics Simulations, and MM-PBSA Calculations
Medicina · Current Computer - Aided Drug Design
Current trends to design antimalarial drugs targeting N -myristoyltransferase
Medicina · Future Microbiology
Targeting Cysteine and Serine Proteases to Discover New Drugs Against Neglected Tropical Diseases
Imunologia e microbiologia · Current Medicinal Chemistry
Molecular Dynamics Simulations and Binding Free Energy Calculations to Discover New Insights into NLRP3 Inhibitors
Farmacologia e toxicologia · Letters in Drug Design & Discovery
Spiro‐Acridine Compound as a Pteridine Reductase 1 Inhibitor: in silico Target Fishing and in vitro Studies
Medicina · ChemMedChem

2023 11

Exploring N-myristoyltransferase as a promising drug target against parasitic neglected tropical diseases
Medicina · European Journal of Medicinal Chemistry
The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors
Farmacologia e toxicologia · Mini-Reviews in Medicinal Chemistry
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation
Medicina · Pharmaceuticals
Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies
Farmacologia e toxicologia · Scientific Reports
Targeting SmCB1: Perspectives and Insights to Design Antischistosomal Drugs
Imunologia e microbiologia · Current Medicinal Chemistry
Overview of the New Bioactive Heterocycles as Targeting Topoisomerase Inhibitors Useful Against Colon Cancer
Bioquímica, genética e biologia molecular · Anti-Cancer Agents in Medicinal Chemistry
Insights on Microsomal Prostaglandin E2 Synthase 1 (mPGES-1) Inhibitors using Molecular Dynamics and MM/PBSA Calculations
Farmacologia e toxicologia · Letters in Drug Design & Discovery
Pharmacokinetic Limitations to Overcome and Enable K777 as a Potential Drug against Chagas Disease
Medicina · Current Pharmaceutical Design
Study of nitrogen heterocycles as DNA/HSA binder, topoisomerase inhibitors and toxicological safety
Bioquímica, genética e biologia molecular · International Journal of Biological Macromolecules
Anti-Inflammatory Activity of N′-(3-(1H-indol-3-yl)benzylidene)-2-cyanoacetohydrazide Derivative via sGC-NO/Cytokine Pathway
Medicina · Pharmaceuticals
C-KIT Receptor Inhibition as a Promising Approach to Design Anticancer Drugs
Imunologia e microbiologia · Current Medicinal Chemistry

2022 5

Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses
Farmacologia e toxicologia · Current Topics in Medicinal Chemistry
Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine–Thiosemicarbazone Derivatives
Bioquímica, genética e biologia molecular · Pharmaceuticals
The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases
Medicina · Pharmaceutics
Would the Development of a Multitarget Inhibitor of 3CLpro and TMPRSS2 be Promising in the Fight Against SARS-CoV-2?
Medicina · Medicinal Chemistry
Topoisomerase Enzyme Inhibitors as Potential Drugs Against Cancer: What Makes Them Selective or Dual? – A Review
Bioquímica, genética e biologia molecular · Current Pharmaceutical Design

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