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Euzébio Guimarães Barbosa

Universidade Federal do Rio Grande do Norte · RN · 27 publicações em 2022–2026

docente de pós-graduaçãoORCID 0000-0002-7685-9618

Computational Drug Discovery MethodsSynthesis and Characterization of Heterocyclic CompoundsHeterocyclic Compound Synthesis and BioactivityResearch on Leishmaniasis StudiesDrug Solubulity and Delivery Systems

Programas de pós-graduação (CAPES)

5BioinformáticaUFRN · docente permanente (2024)4Ciências farmacêuticasUFRN · docente permanente (2024)

Principais coautores no Nordeste tamanho = publicações em comum

Jéssika de Oliveira Viana Karen C. Weber Alessandro Kappel Jordão Ricardo Olímpio de Moura Ádley Antonini Neves de Lima Cláudio Gabriel Lima-Júnior Estela Mariana Guimarães Lourenço Gerd Bruno Rocha Joilly Nilce Santana Gomes Tayná Rodrigues Olegário Wógenes Nunes de Oliveira Addison Ribeiro de Almeida

Orientações concluídas (CAPES)

PLANEJAMENTO DE NOVOS COMPOSTOS DERIVADOS DA TEIXOBACTINA POR SCAFFOLD HOPPING
dissertação · PALOMA KAROLINE DA SILVA BRASIL · CIÊNCIAS FARMACÊUTICAS · 2023
SCAFFOLD REPOSITIONING OF SPIRO-ACRIDINE DERIVATIVES AS FUNGI CHITINASE INHIBITOR BY TARGET FISHING AND IN VITRO STUDIES
tese · JESSIKA DE OLIVEIRA VIANA · BIOINFORMÁTICA · 2023
ESTUDOS IN SILICO DE INIBIDORES ALOSTÉRICOS DO DOMÍNIO AMINO TERMINAL DE RECEPTORES NMDA QUE CONTENHAM A SUBUNIDADE GLUN2B
dissertação · NATALIA VITORIA PEGADO DE MEDEIROS · CIÊNCIAS FARMACÊUTICAS · 2022
MACHINE LEARNING PARA PREDIÇÃO DE REAÇÃO ADVERSA AO MEDICAMENTO: APLICAÇÃO A NEONATOS EM TERAPIA INTENSIVA
dissertação · AMANDA ROSEANE FARIAS DO NASCIMENTO · CIÊNCIAS FARMACÊUTICAS · 2022
MODELAGEM MOLECULAR DE INIBIDORES DOS CANAIS DE TRPM8
dissertação · CARLA CAROLINE RIBEIRO DE MENDONCA · CIÊNCIAS FARMACÊUTICAS · 2022

Publicações recentes

2026 6

Discovery of 6,7-dimethoxyquinazoline-hydrazide hybrids as dual inhibitors of acetylcholinesterase and β-secretase
Medicina · Biochimie
Eyes on the future: PVA-hydrogel lenses as a platform for amphotericin B ocular delivery
Farmacologia e toxicologia · International Journal of Pharmaceutics
Structural Basis for Potent Inhibition of Human DHODH by Quinoline-4-carboxylic Acid Derivatives
Farmacologia e toxicologia · ACS Omega
Insights into a new class of antileishmanial compounds: an in vitro and in silico study of 1,2,4-oxadiazol-5(4H)-one derivatives
Medicina · Bioorganic Chemistry
Bicyclic Lactams From Chiral Imines: Synthesis, Structural Optimization, and Biological Evaluation of Promising Antileishmanial Agents
Medicina · ChemMedChem
Biological evaluation of thiazolopyrimidine derivatives as novel heterocyclic compounds against promastigote and amastigote-like forms of Leishmania infantum and Leishmania tropica
Medicina · Brazilian Journal of Pharmaceutical Sciences

2025 4

In silico target identification and pharmacokinetic profiling of 2-aryl-quinoline-4-carboxylic acid derivatives as potential antileishmanial agents
Farmacologia e toxicologia · Frontiers in Pharmacology
Editorial: Drug discovery for leishmaniasis and chagas disease: compound design and therapeutic strategies
Medicina · Frontiers in Pharmacology
Similarity-Based Profiling of Hydrazone-Containing Scaffolds Active Against Leishmania Amastigotes
Farmacologia e toxicologia · ACS Omega
Targeting Plasmodium Falciparum Asexual and Sexual Stages with Melatonin‐Based Indole Compounds
Medicina · ChemistrySelect

2024 7

Mechanism of action and synergistic effect of Eugenia uniflora extract in Candida spp.
Medicina · PLoS ONE
Development, characterization, and in-vivo evaluation of a novel chitosan: Guar gum particulate system for colonic release of triamcinolone
Farmacologia e toxicologia · Journal of Drug Delivery Science and Technology
Exploiting the biological activities of a lipopeptide extract produced by Bacillus subtilis UFPEDA 438 in light of the SARS-CoV-2 pandemic
Imunologia e microbiologia · Biocatalysis and Agricultural Biotechnology
In Silico Structural Insights and Potential Inhibitor Identification Based on the Benzothiazole Core for Targeting Leishmania major Pteridine Reductase 1
Farmacologia e toxicologia · ACS Omega
Selective inhibition of interleukin 6 receptor decreased inflammatory cytokines and increased proteases in an experimental model of critical calvarial defect
Bioquímica, genética e biologia molecular · Brazilian Journal of Medical and Biological Research
Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms
Medicina · European Journal of Medicinal Chemistry Reports
Spiro‐Acridine Compound as a Pteridine Reductase 1 Inhibitor: in silico Target Fishing and in vitro Studies
Medicina · ChemMedChem

2023 7

The Power of Molecular Dynamics Simulations and Their Applications to Discover Cysteine Protease Inhibitors
Farmacologia e toxicologia · Mini-Reviews in Medicinal Chemistry
Scaffold repositioning of spiro-acridine derivatives as fungi chitinase inhibitor by target fishing and in vitro studies
Farmacologia e toxicologia · Scientific Reports
Flavonoid Derivatives as New Potent Inhibitors of Cysteine Proteases: An Important Step toward the Design of New Compounds for the Treatment of Leishmaniasis
Medicina · Microorganisms
The evaluation of in vitro antichagasic and anti-SARS-CoV-2 potential of inclusion complexes of β- and methyl-β-cyclodextrin with naphthoquinone
Farmacologia e toxicologia · Journal of Drug Delivery Science and Technology
Investigation of the Potential Targets behind the Promising and Highly Selective Antileishmanial Action of Synthetic Flavonoid Derivatives
Medicina · ACS Infectious Diseases
3D-QSARpy: Combining variable selection strategies and machine learning techniques to build QSAR models
Farmacologia e toxicologia · Brazilian Journal of Pharmaceutical Sciences
Machine Learning for Prediction of Adverse Drug Reactions: Application to Neonatal Intensive Care Units
Farmacologia e toxicologia · SSRN Electronic Journal

2022 3

Methyl jasmonate induces selaginellin accumulation in Selaginella convoluta
Ciências agrárias e biológicas · Metabolomics
Intra-hemocoel injection of pseurotin A from Metarhizium anisopliae, induces dose-dependent reversible paralysis in the Greater Wax Moth (Galleria mellonella)
Ciências agrárias e biológicas · Fungal Genetics and Biology
Combining IP3 affinity chromatography and bioinformatics reveals a novel protein-IP3 binding site on Plasmodium falciparum MDR1 transporter
Medicina · Current Research in Microbial Sciences

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