Klinger Antônio da França Rodrigues

Universidade Federal do Delta do Parnaíba · PI · 35 publicações em 2022–2026

docente de pós-graduaçãoORCID 0000-0003-3904-3529

Research on Leishmaniasis StudiesPhytochemistry Medicinal Plant ApplicationsTrypanosoma species research and implicationsEssential Oils and Antimicrobial ActivityComputational Drug Discovery Methods

Programas de pós-graduação (CAPES)

4Ciências biomédicasUFDPAR · docente permanente (2024)5BiotecnologiaUFDPAR · docente permanente (2024)

Principais coautores no Nordeste tamanho = publicações em comum

Raiza Raianne Luz Rodrigues Julyanne Maria Saraiva de Sousa Francisco Jaime Bezerra Mendonça Jefferson Almeida Rocha Vanessa Maria Rodrigues de Souza Paulo Sérgio de Araújo Sousa Airton Lucas Sousa dos Santos Marcus Tullius Scotti Leiz Maria Costa Véras Yasmim Alves Aires Machado Alyne Rodrigues de Araújo Daniel Dias Rufino Arcanjo

Orientações concluídas (CAPES)

AVALIAÇÃO IN VITRO E IN VIVO DA ATIVIDADE ANTILEISHMANIA E MODULAÇÃO IMUNOLÓGICA DO GALATO DE OCTILA
dissertação · WESLEY RODRIGUES DA SILVA · CIÊNCIAS BIOMÉDICAS · 2024
DERIVADO 2-AMINOTIOFÊNICO SB-44: INVESTIGAÇÃO DA ATIVIDADE ANTILEISHMANIA, CITOTOXICIDADE E DOS EFEITOS SOBRE A RESPOSTA IMUNE INATA
dissertação · JULYANNE MARIA SARAIVA DE SOUSA · BIOTECNOLOGIA · 2024
DISTRIBUIÇÃO ESPACIAL E IDENTIFICAÇÃO DE ÁREAS PRIORITÁRIAS PARA VIGILÂNCIA E CONTROLE DA LEISHMANIOSE VISCERAL EM PARNAÍBA, PI, BRASIL
dissertação · RAFAELLA FRANCO RODRIGUES FERRO · CIÊNCIAS BIOMÉDICAS · 2023
SB-200, DERIVADO 2-AMINO-TIOFÊNICO COM POTENCIAL ANTITRYPANOSOMATIDAE E IMUNOMODULADOR
dissertação · JOAO PAULO ARAUJO DE SOUSA · BIOTECNOLOGIA · 2023

Publicações recentes

2026 8

2-Aminothiophene Derivative SB-83 Inhibits Trypanothione Reductase and Modulates Cytokine Production in Trypanosoma cruzi-Infected Cells
Medicina · Pathogens
Limonene and carvacrol combined with drugs that inhibit ergosterol synthesis are potent against Leishmania major
Medicina · Naunyn-Schmiedeberg s Archives of Pharmacology
Efficacy and Pharmacokinetics of Guanidine Derivative LQOF-G2 in an In Vivo Leishmania (Viannia) braziliensis Model
Medicina · Pharmaceuticals
Potential of ethyl acetate and acetone extracts from Montrichardia linifera leaves: Chemical characterization, in vitro study, molecular docking and ADME-TOX
Medicina · Fitoterapia
Octyl Gallate Exhibits Trypanocidal Activity Through Trypanothione Reductase Inhibition and Immunomodulation In Vitro
Medicina · Biomedicines
Evaluation of the antipromastigotes effect of silver nanoparticles synthesized with quaternized angico gum against Leishmania amazonensis
Medicina · International Journal of Biological Macromolecules
Guanidines: Privileged Scaffolds Against Neglected Tropical Diseases: A Review
Medicina · Pharmaceuticals
Insights into a new class of antileishmanial compounds: an in vitro and in silico study of 1,2,4-oxadiazol-5(4H)-one derivatives
Medicina · Bioorganic Chemistry

2025 8

Drug design and synthesis of new N-substituted-thienopyridine based on 2-aminothiophene derivatives as antileishmanial agents
Medicina · Bioorganic & Medicinal Chemistry
Evaluation of SB-83, a 2-amino-thiophene derivative, against Leishmania species that cause visceral leishmaniasis
Medicina · International Immunopharmacology
Exploring Lamiaceae diterpenoids as potential multitarget therapeutics for leishmaniasis and chagas disease
Farmacologia e toxicologia · Molecular Diversity
Characterization and Evaluation of the Biological Activities of Ulvan Extracted from Ulva lactuca with a Focus on the Antiviral Activity Against Herpes Simplex Virus Type 1
Ciências agrárias e biológicas · Journal of Advances in Biology & Biotechnology
Antileishmanial activity of hesperetin on Leishmania donovani, in vitro and in silico inhibition of acetylcholinesterase and investigation of the targets sterol C-24 reductase and N-myristoyltransferase
Medicina · Experimental Parasitology
Yellow mealworm beetle (Tenebrio molitor) larvae as an alternative model for antileishmanial drug evaluation
Medicina · Veterinary Parasitology
Advances in leishmaniasis therapy: preparation, characterization and in vitro evaluation of poly (lactic acid) polymeric nanoparticles with the drug candidate SB-83
Medicina · Nanotechnology
Study of the antileishmanial activity of novel guanidine and hybrid acridine – guanidine compounds
Medicina · European Journal of Medicinal Chemistry

2024 6

Synthesis and characterization of new quaternized galactomannan derivatives with antibacterial activity
Imunologia e microbiologia · International Journal of Biological Macromolecules
Antimicrobial activity of nanoparticles based on carboxymethylated cashew gum and epiisopiloturine: In vitro and in silico studies
Medicina · International Journal of Biological Macromolecules
Anti-Leishmania amazonensis Activity of Morolic Acid, a Pentacyclic Triterpene with Effects on Innate Immune Response during Macrophage Infection
Medicina · Microorganisms
MuDRA‐Based Virtual Screening of Terpenes for Anti‐Leishmania Infantum Activity: In Vitro Validation and Mechanistic Insights from Molecular Docking
Medicina · ChemMedChem
In vitro Antileishmanial Activity and In silico Molecular Modeling Studies of Novel Analogs of Dermaseptins S4 and B2
Medicina · Current Pharmaceutical Biotechnology
AVALIAÇÃO TOXICOLÓGICA AGUDA E ANTI-INFLAMATÓRIA DE Sida santaremnensis H. Monteiro (Malvaceae)
Ciências agrárias e biológicas · Revista Interfaces Saúde Humanas e Tecnologia

2023 8

Cytotoxic and Antileishmanial Effects of the Monoterpene β-Ocimene
Medicina · Pharmaceuticals
Computer-Aided drug design of new 2-amino-thiophene derivatives as anti-leishmanial agents
Farmacologia e toxicologia · European Journal of Medicinal Chemistry
Antileishmanial activity of 2-amino-thiophene derivative SB-200
Medicina · International Immunopharmacology
Influence of Plant Age on Chemical Composition, Antimicrobial Activity and Cytotoxicity of Varronia curassavica Jacq. Essential Oil Produced on an Industrial Scale
Ciências agrárias e biológicas · Agriculture
Evidence of Guanidines Potential against Leishmania (Viannia) braziliensis: Exploring In Vitro Effectiveness, Toxicities and of Innate Immunity Response Effects
Medicina · Biomolecules
Selene-Ethylenelacticamides and N-Aryl-Propanamides as Broad-Spectrum Leishmanicidal Agents
Medicina · Pathogens
Synthetic hydrazones: In silico studies and in vitro evaluation of the antileishmania potential
Medicina · Toxicology in Vitro
Influence of Reduction with NaBH4 and HCl in Obtaining Amino Derivatives of Cashew Gum and Cytotoxic Profile
Ciências agrárias e biológicas · Polymers

2022 5

Molluscicidal and cercaricidal activities of the essential oil of Dysphania ambrosioides (L.) Mosyakin & Clemants: Implications for the control of schistosomiasis
Imunologia e microbiologia · Acta Tropica
Virtual Screening Based on Ligand and Structure with in vitro Assessment of Neolignans against Trypanosoma cruzi
Farmacologia e toxicologia · Journal of the Brazilian Chemical Society
Annonaceae Terpenoids as Potential Leishmanicidal Agents
Medicina · Revista Brasileira de Farmacognosia
Mapeamento científico e tecnológico da goma do cajueiro carboximetilada para o desenvolvimento de nanopartículas poliméricas com aplicação antileishmania
Medicina · Research Society and Development
Natural Products from Annonaceae as Potential Antichagasic Agents
Bioquímica, genética e biologia molecular · ChemMedChem

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