Víctor Diógenes Amaral da Silva

Universidade Federal da Bahia · BA · 33 publicações em 2022–2026

Flavonoids in Medical ResearchNeuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and TreatmentsNeuroprotection in Cerebral IschemiaPhytochemistry Medicinal Plant Applications

Principais coautores no Nordeste tamanho = publicações em comum

Sílvia Lima Costa Maria de Fátima Dias Costa Cleonice Creusa dos Santos Ravena Pereira do Nascimento Balbino Lino dos Santos Fillipe Mendes de Araújo Jorge M. David Juciele Valéria Ribeiro de Oliveira Lívia Bacelar de Jesus Áurea Maria Alves Nunes Almeida Julita Maria Pereira Borges Érica Novaes Soares

Publicações recentes

2026 4

The Flavonoid Apigenin Modulates Oligodendroglial Plasticity and Has a Neuroprotective Effect in Cerebellar Slice Cultures with Oxygen Glucose Deprivation
Medicina · Nutrients
Flavonoid Rutin Reduces Intestinal Inflammation in an Experimental Model of Parkinson's Disease
Medicina · Neurotoxicity Research
Rutin Attenuates Microglial Inflammatory Responses by Promoting M2-like Polarization via GDNF and SHH/GLI-1 Signaling and NLRP3 Inflammasome Inhibition
Neurociência · Neuroglia
Design, Synthesis, In Vitro and In Vivo Evaluation of Novel Anti-Alzheimer’s (1E,4E)-1,5-Bis[(het)aryl]penta-1,4-dien-3-one Derivatives
Medicina · Pharmaceuticals

2025 12

Silodosin as a Novel Inhibitor of Acetylcholinesterase, Butyrylcholinesterase, and BETA-Secretase 1: In Vitro and In Silico Studies
Medicina · ACS Omega
Dichloromethane Extract from Amburana cearensis (Allemão) A.C. Sm. Seeds and Its Coumarin Reduce ROS Production and Protect PC12 Cells Against Glutamate Excitotoxicity and Oxygen-Glucose Deprivation
Medicina · Antioxidants
The Biflavonoid Agathisflavone Regulates Microglial and Astrocytic Inflammatory Profiles via Glucocorticoid Receptor
Neurociência · Molecules
A Narrative Review on the Role of Microbiota and Microglia in Premotor Symptoms of Parkinson’s Disease
Medicina · Neurotoxicity Research
JM-20 administration to animals with lesion of the nigrostriatal dopamine pathway induced by 6-hydroxydopamine, partially reverses motor damage and oxidative stress
Medicina · Neurological Research
Striatal injection of aminochrome in Wistar rats induces early-stage behavioral changes of Parkinson's disease and dopaminergic degeneration in the caudal and medial regions of the nigra pars compacta
Medicina · Neurochemistry International
The Secretome of Brain Endothelial Cells Exposed to the Pyrrolizidine Alkaloid Monocrotaline Induces Astrocyte Reactivity and Is Neurotoxic
Farmacologia e toxicologia · Toxins
Coumarin MAMMEA A/BB cytotoxicity inhibits the chemoresistance and migration of glioblastoma cells in vitro
Medicina · Fitoterapia
The Flavonoid Agathisflavone Attenuates Glia Activation After Mechanical Injury of Cortical Tissue and Negatively Regulates Both NRLP3 and IL-1β Expression
Medicina · International Journal of Molecular Sciences
Natural products research, characterization, and therapeutic role
Farmacologia e toxicologia · Neuroscience
Rosenfeld’s Staining: A Valuable Tool for In Vitro Assessment of Astrocyte and Microglia Morphology
Neurociência · Neuroglia
Ethnopharmacology of neuroprotective compounds in the state of Bahia, Brazil
Medicina · Neuroscience

2024 7

Nicotinic Acetylcholine Receptors in Glial Cells as Molecular Target for Parkinson’s Disease
Medicina · Cells
Role of Glial Cells in Neuronal Function, Mood Disorders, and Drug Addiction
Neurociência · Brain Sciences
Effect of the Flavonoid Rutin on the Modulation of the Myenteric Plexuses in an Experimental Model of Parkinson’s Disease
Medicina · International Journal of Molecular Sciences
The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling
Neurociência · International Journal of Molecular Sciences
Neuroprotective Effect of Flavonoid Agathisflavone in the Ex Vivo Cerebellar Slice Neonatal Ischemia
Medicina · Molecules
Correlational assessment of the effects of JM-20 in a rat model of parkinsonism
Medicina · Behavioural Brain Research
Three New Polyprenylated Benzophenone Derivatives Isolated from Clusia burle‐marxii
Farmacologia e toxicologia · Chemistry & Biodiversity

2023 4

Protective Effects of Flavonoid Rutin Against Aminochrome Neurotoxicity
Medicina · Neurotoxicity Research
The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome
Neurociência · Pharmaceutics
Impact of Plant-Derived Compounds on Amyotrophic Lateral Sclerosis
Medicina · Neurotoxicity Research
Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia
Neurociência · BMC Complementary Medicine and Therapies

2022 6

Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma
Medicina · Pharmaceutics
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Medicina · Neurotoxicity Research
Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats
Medicina · Frontiers in Pharmacology
Monocrotaline induces acutely cerebrovascular lesions, astrogliosis and neuronal degeneration associated with behavior changes in rats: A model of vascular damage in perspective
Farmacologia e toxicologia · NeuroToxicology
Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With Neospora caninum
Neurociência · International Journal of Tryptophan Research
Astrocyte Reaction to Catechol-Induced Cytotoxicity Relies on the Contact with Microglia Before Isolation
Neurociência · Neurotoxicity Research

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