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MC

Maria de Fátima Dias Costa

Universidade Federal da Bahia · BA · 23 publicações em 2022–2026

ORCID 0000-0003-0916-2893

Flavonoids in Medical ResearchNeuroinflammation and Neurodegeneration MechanismsGlioma Diagnosis and TreatmentPhytochemistry Medicinal Plant ApplicationsTravel Writing and Literature

Principais coautores no Nordeste tamanho = publicações em comum

Sílvia Lima Costa Víctor Diógenes Amaral da Silva Cleonice Creusa dos Santos Balbino Lino dos Santos Bruno Solano de Freitas Souza Jorge M. David Érica Novaes Soares Fillipe Mendes de Araújo Ravena Pereira do Nascimento Deivison Silva Argolo Karina Costa da Silva Lívia Bacelar de Jesus

Publicações recentes

2026 2

The Flavonoid Rutin Enhances Temozolomide Sensitivity in Glioblastoma Spheroids by Modulating Chemoresistance via PI3K/AKT, STAT3, Redox and Kynurenine Pathways, and Altering ECM Remodeling Associated with Reduced Migration
Medicina · Antioxidants
Rutin Attenuates Microglial Inflammatory Responses by Promoting M2-like Polarization via GDNF and SHH/GLI-1 Signaling and NLRP3 Inflammasome Inhibition
Neurociência · Neuroglia

2025 7

Tryptophan Metabolism Through the Kynurenine Pathway in Glial Cells
Neurociência · Neuroglia
Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation
Medicina · Molecules
Apigenin Induces Autophagy and Apoptosis in Chemoresistant Glioblastoma Cells and Inhibits Tumorigenicity Associated with Regulation of Immunomodulatory Proteins and Glial Cells Response
Medicina · Cells
Dichloromethane Extract from Amburana cearensis (Allemão) A.C. Sm. Seeds and Its Coumarin Reduce ROS Production and Protect PC12 Cells Against Glutamate Excitotoxicity and Oxygen-Glucose Deprivation
Medicina · Antioxidants
Synthesis of Naringenin and Senecioic Acid Ester Derivatives and Biological Evaluation of the Astrocyte Antioxidant Mechanism and Reactivity After Inflammatory Stimulus
Medicina · International Journal of Molecular Sciences
Agathisflavone Modulates the Kynurenine Pathway and Glial Inflammatory Responses with Implications for Neuroprotection
Neurociência · International Journal of Molecular Sciences
Rosenfeld’s Staining: A Valuable Tool for In Vitro Assessment of Astrocyte and Microglia Morphology
Neurociência · Neuroglia

2024 2

Effect of the Flavonoid Rutin on the Modulation of the Myenteric Plexuses in an Experimental Model of Parkinson’s Disease
Medicina · International Journal of Molecular Sciences
The Phytochemical Agathisflavone Modulates miR146a and miR155 in Activated Microglia Involving STAT3 Signaling
Neurociência · International Journal of Molecular Sciences

2023 6

Protective Effects of Flavonoid Rutin Against Aminochrome Neurotoxicity
Medicina · Neurotoxicity Research
The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome
Neurociência · Pharmaceutics
THE FLAVONOID AGATHISFLAVONE DIRECTS MICROGLIA TO AN ANTIOXIDANT AND ANTI-INFLAMMATORY STATUS VIA REGULATION OF NLRP3 INFLAMMASOME, THAT IS NEUROPROTECTIVE.
Neurociência · IBRO Neuroscience Reports
Amburana cearensis seed extract stimulates astrocyte glutamate homeostatic mechanisms in hippocampal brain slices and protects oligodendrocytes against ischemia
Neurociência · BMC Complementary Medicine and Therapies
TRANSMISSÃO VERTICAL, RETENÇÃO E ADESÃO AO TRATAMENTO DO HIV NO CONTEXTO DA MATERNIDADE EM UM CENTRO DE REFERÊNCIA, SALVADOR, BAHIA
Medicina · The Brazilian Journal of Infectious Diseases
MOLECULAR MECHANISMS IN PARKINSON’S DISEASE AND POTENTIAL USE OF NATURAL COMPOUNDS
Medicina · IBRO Neuroscience Reports

2022 6

Neuroimmunomodulatory Properties of Flavonoids and Derivates: A Potential Action as Adjuvants for the Treatment of Glioblastoma
Medicina · Pharmaceutics
Neurological Infection, Kynurenine Pathway, and Parasitic Infection by Neospora caninum
Neurociência · Frontiers in Immunology
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Medicina · Neurotoxicity Research
Agathisflavone as a Single Therapy or in Association With Mesenchymal Stem Cells Improves Tissue Repair in a Spinal Cord Injury Model in Rats
Medicina · Frontiers in Pharmacology
Activation of the Kynurenine Pathway and Production of Inflammatory Cytokines by Astrocytes and Microglia Infected With Neospora caninum
Neurociência · International Journal of Tryptophan Research
Astrocyte Reaction to Catechol-Induced Cytotoxicity Relies on the Contact with Microglia Before Isolation
Neurociência · Neurotoxicity Research

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