Emanuel Paula Magalhães

Universidade Federal do Ceará · CE · 37 publicações em 2022–2026

Trypanosoma species research and implicationsHeterocyclic Compound Synthesis and BioactivityAcute Kidney Injury ResearchChemotherapy-induced organ toxicity mitigationComputational Drug Discovery Methods

Principais coautores no Nordeste tamanho = publicações em comum

Alice Maria Costa Martins Ramon Róseo Paula Pessoa Bezerra de Menezes Márcia Machado Marinho Tiago Lima Sampaio Emmanuel Silva Marinho Hélcio Silva dos Santos Bruna Ribeiro Duque Lyanna Rodrigues Ribeiro Mac Dionys Rodrigues da Costa Dânya Bandeira Lima Francisco Wagner Queiroz Almeida-Neto Matheus Nunes da Rocha

Publicações recentes

2026 7

Tempo de Isquemia Fria no Transplante Renal: Fisiopatologia, Impacto Clínico e Estratégias Emergentes de Preservação – Uma Revisão Narrativa
Medicina · Brazilian Journal of Transplantation
Evaluation of Chalcone ( E )-3-(4-Fluorophenyl)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-prop-2-en-1-one against Trypanosoma cruzi (Y Strain): In Vitro Assay, In Silico Drug-Target Analysis, and MPO-Based Drug Likeness
Medicina · ACS Omega
Evaluation of the in vitro activity of synthetic derivatives of N-cyclohexyl-3-(3-methylphenyl)-1,2,4-oxadiazole-5-amine on the strain y of Trypanosoma cruzi and an in vivo toxicity study
Medicina · Memórias do Instituto Oswaldo Cruz
Cold Ischemia Time in Kidney Transplantation: Pathophysiology, Clinical Impact, and Emerging Preservation Strategies – A Narrative Review
Medicina · Brazilian Journal of Transplantation
[Lys3, Lys4] M-PONTX-Dq3a [1–15]: a selective dinoponeratoxin-derived peptide that disrupts parasite membranes and inhibits TcGAPDH activity in Trypanosoma cruzi
Medicina · Toxicon
Susceptibility profile of Staphylococcus aureus isolates in blood cultures from a tertiary hospital - comparison of methods for determination of minimum inhibitory concentration of vancomycin
Medicina · Journal of Health & Biological Sciences
Electron donating and withdrawing groups affect the antioxidant activity of 4′-aminochalcones on gentamicin-induced kidney cell injury
Farmacologia e toxicologia · Biological Chemistry

2025 8

In vitro antitumor and immunomodulatory activities of 1,2,4-oxadiazole derivatives
Imunologia e microbiologia · Biochemistry and Biophysics Reports
Resveratrol’s potential in the prevention and treatment of neurodegenerative diseases: molecular mechanisms
Medicina · Exploration of Neuroprotective Therapy
Evaluation of the Anxiolytic and Anticonvulsant Effect of Marlierea eugeniopsoides Essential Oils and Its Majority Constituents in Adult Zebrafish
Medicina · Chemistry & Biodiversity
Cymbopogon citratus Essential Oil Protects Tubular Renal Cells against Ischemia/Reoxygenation Injury - Involvement Nrf2/Keap1 Pathway
Medicina · Brazilian Archives of Biology and Technology
Efeito da imunossupressão sobre a atividade de enzimas de avaliação da função hepática pós-transplante renal em hospital universitário de Fortaleza
Medicina · Journal of Health & Biological Sciences
A phenolic ether 2-methoxy-carvacrol isolated from Rhabdocaulon lavanduloides (Benth) Epling. (Lamiaceae): New crystal structure, Hirshfeld surface, quantum chemical calculation, anxiolytic and anticonvulsant potential in zebrafish, and molecular docking of GABAA receptor
Medicina · Journal of Molecular Structure
Leishmanicidal effect of dinoponeratoxin peptides from Dinoponera quadriceps
Medicina · Toxicon
TcGAPDH peptidic inhibitors derived from dinoponeratoxin M-PONTX-Dq4e with trypanocidal effect
Medicina · Toxicon

2024 5

Insights of potential trypanocidal effect of the synthetic derivative (2E)-1-(4-aminophenyl)-3-(2,4-dichlorophenyl)prop-2-en-1-one: in vitro assay, MEV analysis, quantum study, molecular docking, molecular dynamics, MPO analysis, and predictive ADMET
Medicina · Naunyn-Schmiedeberg s Archives of Pharmacology
Synthesis, vibrational analysis, thermal analysis, quantum-chemical calculation, molecular docking and dynamics, DMPK and evaluation of the antichagasic potential of a fluorinated chalcone
Medicina · Journal of Molecular Structure
Correlation of Apolipoprotein a-i with Renal Function in Diabetic Patients
Medicina · Brazilian Archives of Biology and Technology
Single nucleotide polymorphisms in apolipoprotein A-I (rs670) and B (rs693) associated with serum lipoproteins and endothelial activation in COVID-19 outpatients
Medicina · Brazilian Journal of Pharmaceutical Sciences
Bioprospecting hydroxylated chalcones in in vitro model of ischemia-reoxygenation and probing NOX4 interactions via molecular docking
Medicina · Biological Chemistry

2023 6

GABA A and serotonergic receptors participation in anxiolytic effect of chalcones in adult zebrafish
Neurociência · Journal of Biomolecular Structure and Dynamics
Piplartine-Inspired 3,4,5-Trimethoxycinnamates: Trypanocidal, Mechanism of Action, and In Silico Evaluation
Medicina · Molecules
Trypanocidal potential of synthetic p-aminochalcones: In silico and in vitro evaluation
Medicina · Bioorganic Chemistry
Piplartine Synthetic Analogs: In Silico Analysis and Antiparasitic Study against Trypanosoma cruzi
Medicina · Applied Sciences
Elongation on Aliphatic Chain Improves Selectivity of 2-Hydroxy-3,4,6-Trimethoxyphenyl Chalcone on Trypanosoma Cruzi
Medicina · Future Medicinal Chemistry
Effect from dinoponeratoxin M-PONTXDq3a arginine and lysine substituted analogues against Staphylococcus aureus strains
Imunologia e microbiologia · Toxicon

2022 11

Vitamin D3 actions on astrocyte cells: A target for therapeutic strategy in Parkinson’s disease?
Medicina · Neuroscience Letters
Chloride substitution on 2-hydroxy-3,4,6-trimethoxyphenylchalcones improves in vitro selectivity on Trypanosoma cruzi strain Y
Medicina · Chemico-Biological Interactions
Quantum mechanical, molecular docking, molecular dynamics, ADMET and antiproliferative activity on Trypanosoma cruzi (Y strain) of chalcone ( E )-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(3-nitrophenyl)prop-2-en-1-one derived from a natural product
Farmacologia e toxicologia · Physical Chemistry Chemical Physics
Rational design of a trypanocidal peptide derived from Dinoponera quadriceps venom
Medicina · European Journal of Medicinal Chemistry
Antiparasitary and antiproliferative activities in vitro of a 1,2,4-oxadiazole derivative on Trypanosoma cruzi
Medicina · Parasitology Research
1α,25-Dihydroxyvitamin D3 (VD3) Shows a Neuroprotective Action Against Rotenone Toxicity on PC12 Cells: An In Vitro Model of Parkinson’s Disease
Medicina · Neurochemical Research
Tyramine exerts hypolipidemic and anti-obesity effects in vivo
Farmacologia e toxicologia · Brazilian Journal of Pharmaceutical Sciences
Antichagasic evaluation, molecular docking and ADMET properties of the chalcone (2 E )-3-(2-fluorophenyl)-1-(2-hydroxy- 3,4,6-trimethoxyphenyl)prop-2-en-1-one against Trypanosoma cruzi
Medicina · Journal of Biomolecular Structure and Dynamics
N-Methyl-(2S, 4R)-trans-4-hydroxy-L-proline, the major bioactive compound from Sideroxylon obtusifolium, attenuates pilocarpine-induced injury in cultured astrocytes
Medicina · Brazilian Journal of Medical and Biological Research
Preliminary Study for New Markers of Early Tubuloglomerular Injury and Renal Inflammation in Patients with Visceral Leishmaniasis Receiving Liposomal Amphotericin B Treatment
Medicina · American Journal of Tropical Medicine and Hygiene
Inhibition potential of the major secondary metabolites isolated from anacardium occidentale against Mpro enzyme from COVID-19 virus using molecular docking and dynamics studies
Farmacologia e toxicologia · Journal of Analytical & Pharmaceutical Research

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