Janaína Esmeraldo Rocha

Universidade Regional do Cariri · CE · 48 publicações em 2022–2026

Essential Oils and Antimicrobial ActivityAntibiotic Resistance in BacteriaAntimicrobial Resistance in StaphylococcusAntimicrobial agents and applicationsDrug Transport and Resistance Mechanisms

Principais coautores no Nordeste tamanho = publicações em comum

Henrique Douglas Melo Coutinho Thiago Sampaio de Freitas Hélcio Silva dos Santos Emmanuel Silva Marinho Irwin Rose Alencar de Menezes José Weverton Almeida‐Bezerra Márcia Machado Marinho Alexandre Magno Rodrigues Teixeira Raimundo Luíz Silva Pereira Cícera Datiane de Morais Oliveira–Tintino José Maria Barbosa‐Filho José Thyálisson da Costa Silva

Publicações recentes

2026 11

Adjuvant Activity and Resistance-Modifying Capacity of a Novel Heterocyclic Hydrazone Derived from the Drug Hydralazine in NorA and MepA Efflux Pumps of Staphylococcus aureus
Medicina · Drugs and Drug Candidates
Lupeol as a modulator of bacterial resistance mediated by the MepA efflux pump in Staphylococcus aureus
Medicina · Naunyn-Schmiedeberg s Archives of Pharmacology
Metronidazole and Eugenol Hybrids as an Alternative Against Multidrug‐Resistant Bacteria
Ciências agrárias e biológicas · ChemistrySelect
Modifying Effect of the Antibiotic Action, Membrane Permeability, and ADMET/Toxicity Profile of the Fixed Oil From the Pulp of Mauritia Flexuosa F.L. (Arecaceae)
Ciências agrárias e biológicas · Chemistry & Biodiversity
Modulatory effect of Canavalia gladiata lectin on quinolone activity against multidrug-resistant and efflux pump-positive Staphylococcus aureus
Medicina · Frontiers in Pharmacology
Evaluation of the effects of hybrids of metronidazole and eugenol analogues as inhibitors of the Staphylococcus aureus NorA efflux pump: an in vitro and in silico analysis
Medicina · Folia Microbiologica
In Vitro and In Silico Evaluation of the Potentiating Effect of Thiadiazine Derivatives Against Multidrug-Resistant (MDR) Bacterial Strains
Medicina · Antibiotics
Himatanthus drasticus (Mart.) Plumel (APOCYNACEAE): phytochemical profile, evaluation of antibacterial and drug-potentiating activity, and toxicity of stem bark extracts
Ciências agrárias e biológicas · Vegetos
Synthesis, Structural Characterization, and Evaluation of the Antibacterial Activity of Chalcones Against Staphylococcus aureus Strains Overexpressing the NorA and MepA Efflux Pumps: An In Vitro, In Silico, and Molecular Approach
Medicina · ChemistrySelect
Evaluation of the antimicrobial and NorA and MepA efflux pump inhibitory activity of a hydrazone derivative of hydralazine against Staphylococcus aureus
Medicina · Archives of Microbiology
Establishing a Zebrafish (Danio rerio) infection model to assess antimicrobial treatment efficacy against Staphylococcus aureus expressing the NorA efflux pump
Medicina · Biologia

2025 14

ADME/Tox study and the effect of β-Caryophyllene on the resistant strain of Staphylococcus aureus carrying the QacA/B efflux pump gene
Ciências agrárias e biológicas · Toxicology Reports
Evaluation of the intrinsic antibacterial and antibiotic potentiating activity against antibiotic resistance in Staphylococcus aureus and inhibition of the NorA and MepA efflux pumps by a hydrazone derivative of isoniazid
Medicina · Microbial Pathogenesis
Evaluation of the Efflux Pump Inhibition Activity of Thiadiazine-Derived Compounds Against the Staphylococcus aureus 1199B Strain
Medicina · Pharmaceuticals
Integrated in Vitro, in Vivo, Molecular Docking, and ADMET in Silico Assessment of β-Caryophyllene as a NorA Efflux Pump inhibitor in Resistant Staphylococcus Aureus (MRSA)
Medicina · Current Microbiology
Electronic properties and adjuvant effect of riparins I-IV: Inhibition of β-lactamase and QacC efflux pump in Staphylococcus aureus K4100
Medicina · Biochemical and Biophysical Research Communications
In Vitro and In Silico Study of the Inhibitory Potential of Riparins I, II, III, and IV on the NorA Efflux Pump of Staphylococcus aureus
Medicina · ChemistrySelect
Chemical composition and In Vitro evaluation of the susceptibility of bacterial biofilms to the essential oil of Syzygium cumini (L.) Skeels
Ciências agrárias e biológicas · Food and Humanity
Antibacterial and Antibiotic‐Enhancing Activity of 3‐Hydroxy‐4‐methoxycinnamic Acid: Experimental Data and In Silico Predictions
Ciências agrárias e biológicas · ChemistrySelect
Antibacterial Mechanisms of 4-Chlorobenzyl p-Coumarate: Inhibition of MepA and NorA Efflux Pumps
Medicina · Future Pharmacology
Investigation of Phytol as an Inhibitor of the Efflux Pump (QacA/B) in Staphylococcus aureus: in silico and in vitro Studies
Medicina · Pharmaceutical Research
Potentiating-antibiotic and antibacterial properties of Luetzelburgia auriculata (ALLEMÃO) Ducke against MDR bacterial strains
Ciências agrárias e biológicas · Vegetos
Chemical composition and adjuvant action of Cordia oncocalyx Allemão (Boraginaceae) leaf extract in enhancing the antifungal effect of fluconazole against Candida spp
Medicina · Journal of Herbal Medicine
Antibacterial and potentiating activity of 3-methoxycinnamic acid on antibiotics: an in vitro and in silico approach
Medicina · FEMS Microbiology Letters
Antibacterial and Potentiating Activity of the Essential Oil of Citrus aurantiifolia (Christm.) Swingle (Rutaceae)
Ciências agrárias e biológicas · SVOA Microbiology

2024 6

Analysis of the Antibiotic-Potentiating Activity, Absorption, Distribution, Metabolism, and Excretion (ADME) and the Molecular Docking Properties of Phytol Against Multi-Drug-Resistant (MDR) Strains
Ciências agrárias e biológicas · Antibiotics
Unlocking bacterial defense: Exploring the potent inhibition of NorA efflux pump by coumarin derivatives in Staphylococcus aureus
Medicina · Microbial Pathogenesis
Quantum-chemical calculation, antibiotic potentiating activity, evaluation of efflux pump inhibition against S. aureus multi-resistant strains and molecular docking of the drugs isoniazid and hydralazine
Medicina · Journal of Molecular Structure
Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction
Medicina · Pharmaceutics
Molecular docking and antibacterial and antibiotic-modifying activities of synthetic chalcone (2E)-1-(3′-aminophenyl)-3-(4-dimethylaminophenyl)-prop-2-en-1-one in a MepA efflux pump-expressing Staphylococcus aureus strain
Medicina · Folia Microbiologica
Structural Characterization, Dft Calculations, Admet Studies, Antibiotic Potentiating Activity, Evaluation of Efflux Pump Inhibition of Hydrazone Derivative of the Drug Hydralazine
Medicina · SSRN Electronic Journal

2023 3

Evaluation of the antibacterial and inhibitory activity of the MepA efflux pump of Staphylococcus aureus by riparins I, II, III, and IV
Medicina · Archives of Biochemistry and Biophysics
In vitro and in silico evidences about the inhibition of MepA efflux pump by coumarin derivatives
Medicina · Microbial Pathogenesis
Synthesis, structural, characterization, antibacterial and antibiotic modifying activity, ADMET study, molecular docking and dynamics of chalcone ( E )-1-(4-aminophenyl)-3-(4-nitrophenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps
Medicina · Journal of Biomolecular Structure and Dynamics

2022 14

Ferulic acid derivatives inhibiting Staphylococcus aureus tetK and MsrA efflux pumps
Medicina · Biotechnology Reports
Evaluation of antibacterial and toxicological activities of essential oil of Ocimum gratissimum L. and its major constituent eugenol
Ciências agrárias e biológicas · Food Bioscience
Antibacterial effect and evaluation of the inhibitory effect against efflux pump in Staphylococcus aureus by abietic acid: In vitro and in silico assays
Medicina · Process Biochemistry
Antibacterial and antibiotic modifying activity of chalcone (2E)-1-(4′-aminophenyl)-3-(4-methoxyphenyl)-prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps: In vitro and in silico approaches
Medicina · Microbial Pathogenesis
HPLC–DAD analysis and antimicrobial activities of Spondias mombin L. (Anacardiaceae)
Ciências agrárias e biológicas · 3 Biotech
Anti-inflammatory effect, antibiotic potentiating activity against multidrug-resistant strains of Escherichia coli and Staphylococcus aureus, and evaluation of antibiotic resistance mechanisms by the ibuprofen derivative methyl 2-(-4-isobutylphenyl)propanoate
Medicina · Microbial Pathogenesis
ADMET study, spectroscopic characterization and effect of synthetic nitro chalcone in combination with norfloxacin, ciprofloxacin, and ethidium bromide against Staphylococcus aureus efflux pumps
Medicina · Fundamental and Clinical Pharmacology
Mechanisms of Actions Involved in The Antinociceptive Effect of Estragole and its β-Cyclodextrin Inclusion Complex in Animal Models
Medicina · Plants
Potentiation of antibiotic activity, and efflux pumps inhibition by (2E)‐1‐(4‐aminophenyl)‐3‐(4‐fluorophenyl)prop‐2‐en‐1‐one
Medicina · Fundamental and Clinical Pharmacology
Antibacterial effect, efflux pump inhibitory (NorA, TetK and MepA) of Staphylococcus aureus and in silico prediction of α, β and δ-damascone compounds
Medicina · Arabian Journal of Chemistry
Photobiological effect of eugenol‐derived 3‐benzoylcoumarin associated with led lights against MDR microorganisms
Bioquímica, genética e biologia molecular · Fundamental and Clinical Pharmacology
Dihydroeugenol derivatives associated with blue LED light: A different form to face multidrug resistant (MDR) bacteria
Bioquímica, genética e biologia molecular · Microbial Pathogenesis
Chemical characterization and antimicrobial potential of the essential oil obtained from the leaves of Piper xylosteoides (Kunth) Steud.
Ciências agrárias e biológicas · South African Journal of Botany
Resistência a antibióticos mediada por plasmídeos / Plasmide-mediated resistance to antibiotics
Medicina · Brazilian Journal of Health Review

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