Isaac Moura Araújo

Universidade Regional do Cariri · CE · 46 publicações em 2022–2026

Antibiotic Resistance in BacteriaEssential Oils and Antimicrobial ActivityPhytochemistry Medicinal Plant ApplicationsAntimicrobial agents and applicationsAntimicrobial Resistance in Staphylococcus

Principais coautores no Nordeste tamanho = publicações em comum

Henrique Douglas Melo Coutinho Cícera Datiane de Morais Oliveira–Tintino Irwin Rose Alencar de Menezes Saulo Relison Tintino Hélcio Silva dos Santos Sheila Alves Gonçalves Ana Carolina Justino de Araújo Cícera Laura Roque Paulo Janaína Esmeraldo Rocha Raimundo Luíz Silva Pereira Emmanuel Silva Marinho João Arthur de Oliveira Borges

Publicações recentes

2026 8

In Vitro and In Silico Evaluation of the Potentiating Effect of Thiadiazine Derivatives Against Multidrug-Resistant (MDR) Bacterial Strains
Medicina · Antibiotics
Chemical synthesis and evaluation of the antibacterial activity of the amino chalcone in efflux pump-carrying strains
Medicina · FEMS Microbiology Letters
Daidzin and Phytol Enhance the Sedative Effect of Diazepam and the Anesthetic Effects of Thiopental Sodium: In Vivo and Computational Assessments
Medicina · Iranian Journal of Science
Modifying Effect of the Antibiotic Action, Membrane Permeability, and ADMET/Toxicity Profile of the Fixed Oil From the Pulp of Mauritia Flexuosa F.L. (Arecaceae)
Ciências agrárias e biológicas · Chemistry & Biodiversity
Aqueous Extract of Luffa cylindrica: Modulation of Antibiotic Action and Antioxidant and Cytoprotective Evaluation
Ciências agrárias e biológicas · Scientific Electronic Archives
Adjuvant Effect of Meldrum’s Acid Derivatives on Antibiotic Activity Against Multidrug-Resistant Bacteria
Imunologia e microbiologia · International Journal of Molecular Sciences
Modulatory effect of Canavalia gladiata lectin on quinolone activity against multidrug-resistant and efflux pump-positive Staphylococcus aureus
Medicina · Frontiers in Pharmacology
Atividade antibacteriana e modificação da ação antibiótica do citral frente a cepas de Acinetobacter baumannii
Ciências agrárias e biológicas · Scientific Electronic Archives

2025 11

Assessment of MepA inhibition potential using thiadiazine derivatives through fluorometry, docking, and qPCR
Medicina · Gene Reports
Anticancer Efficacy of Decursin: A Comprehensive Review with Mechanistic Insights
Ciências agrárias e biológicas · Future Pharmacology
Pharmacology, toxicology and homeopathy of Luffa operculata (L.) Cogniaux (Cucurbitaceae): Integrative review
Ciências agrárias e biológicas · Toxicon
Evaluation of the Activity of Amino Chalcone Against Staphylococcus Strains Harboring Efflux Pumps
Medicina · Pharmaceuticals
Investigation of the vasodilatory, tocolytic and spasmolytic effects of rutin on Wistar rats tissues
Medicina · Pharmacological Research - Natural Products
Antibacterial Activity of Chalcone (2E)-3-({4-[(2E)-3-(4-Nitrophenyl) prop-2-enol] phenyl}carbamoyl) prop-2-enoic acid and Its Effect Against Staphylococcus aureus Carrying Efflux Pump and β-Lactamase
Medicina · Current Microbiology
Antibacterial and antibiotic modulating activity of the aqueous extract of the fruits of Luffa operculata Cogn.
Ciências agrárias e biológicas · The Microbe
Potentiating-antibiotic and antibacterial properties of Luetzelburgia auriculata (ALLEMÃO) Ducke against MDR bacterial strains
Ciências agrárias e biológicas · Vegetos
Effects of linalyl acetate, (-)-menthone, and myrtenol against bacterial strains carrying efflux pumps and toxicity against Drosophila melanogaster
Ciências agrárias e biológicas · Pharmacological Research - Natural Products
Antibacterial and potentiating activity of 3-methoxycinnamic acid on antibiotics: an in vitro and in silico approach
Medicina · FEMS Microbiology Letters
Antibacterial and Antibiotic‐Enhancing Activity of 3‐Hydroxy‐4‐methoxycinnamic Acid: Experimental Data and In Silico Predictions
Ciências agrárias e biológicas · ChemistrySelect

2024 8

Analysis of the Antibiotic-Potentiating Activity, Absorption, Distribution, Metabolism, and Excretion (ADME) and the Molecular Docking Properties of Phytol Against Multi-Drug-Resistant (MDR) Strains
Ciências agrárias e biológicas · Antibiotics
Thiazine-derived compounds in inhibiting efflux pump in Staphylococcus aureus K2068, mepA gene expression, and membrane permeability alteration
Medicina · Biomedicine & Pharmacotherapy
In vitro and in silico effect of meldrum's acid-derived compounds on Staphylococcus aureus strains as NorA efflux pump inhibitors
Medicina · Biophysical Chemistry
Phytochemical characterization, toxicity and pharmacological profile of the central effects of the fixed fruit pulp oil of Mauritia flexuosa L.F. (buriti)
Medicina · Fitoterapia
Antibacterial and Inhibitory Activity of Nora and Mepa Efflux Pumps of Estragole Complexed to β-Cyclodextrin (ES/β-CD) In Vitro Against Staphylococcus aureus Bacteria, Molecular Docking and MPO-Based Pharmacokinetics Prediction
Medicina · Pharmaceutics
Chemical Characterization and Biological Activity of Varronia curassavica Jacq. Essential Oil (Boraginaceae) and In Silico Testing of α-Pinene
Ciências agrárias e biológicas · Analytica—A Journal of Analytical Chemistry and Chemical Analysis
Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors
Medicina · Current Microbiology
Evaluating efflux pump inhibition in Staphylococcus aureus 1199B strain using thiadiazine-derived compounds: In vitro and in silico approaches
Medicina · Biochimie

2023 12

Assessment of Quercetin Antiemetic Properties: In Vivo and In Silico Investigations on Receptor Binding Affinity and Synergistic Effects
Medicina · Plants
Antibacterial Activity of the Essential Oil of Piper tuberculatum Jacq. Fruits against Multidrug-Resistant Strains: Inhibition of Efflux Pumps and β-Lactamase
Ciências agrárias e biológicas · Plants
Sclareol exerts synergistic antidepressant effects with quercetin and caffeine, possibly suppressing GABAergic transmission in chicks
Medicina · Biomedicine & Pharmacotherapy
Antibacterial activity and anxiolytic-like effect of Ziziphus joazeiro Mart. leaves in adult zebrafish (Danio rerio)
Ciências agrárias e biológicas · Fish and Shellfish Immunology Reports
Evaluation of the antibacterial and inhibitory activity of the MepA efflux pump of Staphylococcus aureus by riparins I, II, III, and IV
Medicina · Archives of Biochemistry and Biophysics
Bioactivities and ethnopharmacology of Sesamum indicum L seed oil
Ciências agrárias e biológicas · LWT
Chemical composition and antibacterial effects of Etlingera elatior (Jack) R.M. Smith against Staphylococcus aureus efflux pumps
Ciências agrárias e biológicas · Chemico-Biological Interactions
Eucalyptol prevents pilocarpine-induced seizure and neuronal damage in mice, through the cholinergic, monoaminergic and antioxidant pathways
Medicina · Food Bioscience
The preeclampsia condition alters external potassium-evoked contraction of human umbilical vessels
Medicina · Placenta
Antibacterial and Toxic Activity of Geopropolis Extracts from Melipona subnitida (Ducke, 1910) (Hymenoptera: Apidae) and Scaptotrigona depilis (Moure, 1942) (Hymenoptera: Apidae)
Ciências agrárias e biológicas · Chemistry & Biodiversity
Use of essential oils from plants of Araripe National Forest against Aedes aegypti (Diptera: Culicidae)
Ciências agrárias e biológicas · Brazilian Journal of Biology
Meldrum's acid derivates are MepA efflux pump inhibitors: In vitro and in silico essays
Medicina · Journal of Basic Microbiology

2022 7

Anxiolytic-like Effect of Quercetin Possibly through GABA Receptor Interaction Pathway: In Vivo and In Silico Studies
Medicina · Molecules
Antifungal Effect and Inhibition of the Virulence Mechanism of D-Limonene against Candida parapsilosis
Medicina · Molecules
GC–MS analysis, and evaluation of protective effect of Piper chaba stem bark against paracetamol-induced liver damage in Sprague-Dawley rats: Possible defensive mechanism by targeting CYP2E1 enzyme through in silico study
Farmacologia e toxicologia · Life Sciences
Bioactive Natural Products for Chemical Control of Microorganisms: Scientific Prospecting (2001–2021) and Systematic Review
Ciências agrárias e biológicas · Molecules
Ethnomedicinal Uses, Phytochemistry, and Therapeutic Potentials of Litsea glutinosa (Lour.) C. B. Robinson: A Literature-Based Review
Ciências agrárias e biológicas · Pharmaceuticals
Possible mechanisms involved in the neuroprotective effect of Trans,trans-farnesol on pilocarpine-induced seizures in mice
Medicina · Chemico-Biological Interactions
Modification of Antibiotic Activity by Fixed Oil of the Artocarpus heterophyllus Almond against Standard and Multidrug-Resistant Bacteria Strains
Ciências agrárias e biológicas · Biology

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