João Xavier de Araújo‐Júnior

Universidade Federal de Alagoas · AL · 29 publicações em 2022–2026

Synthesis and Characterization of Heterocyclic CompoundsComputational Drug Discovery MethodsHeterocyclic Compound Synthesis and BioactivityPhytochemistry Medicinal Plant ApplicationsMedicinal Plant Research

Principais coautores no Nordeste tamanho = publicações em comum

Edeildo Ferreira da Silva‐Júnior Francisco Jaime Bezerra Mendonça Igor José dos Santos Nascimento Henrique Douglas Melo Coutinho Johnnatan Duarte de Freitas Thiago Mendonça de Aquino Ana Carolina Justino de Araújo Priscilla Ramos Freitas Cícera Datiane de Morais Oliveira–Tintino Emmanuel Silva Marinho Hélcio Silva dos Santos Irwin Rose Alencar de Menezes

Publicações recentes

2026 6

QSAR-based drug discovery of 2-((4-Imino-3,4-dihydroquinazolin-2-yl)thio-substituted analogs targeting Mycobacterium tuberculosis
Farmacologia e toxicologia · Bioorganic & Medicinal Chemistry
Inhibitory effects of thiophene-2-thiazole hybrids against sensitive strains and resistant clinical isolates of Mycobacterium tuberculosis
Medicina · Bioorganic & Medicinal Chemistry Letters
In Vitro and In Silico Evaluation of the Potentiating Effect of Thiadiazine Derivatives Against Multidrug-Resistant (MDR) Bacterial Strains
Medicina · Antibiotics
Microparticles of greenish-brown propolis extract: phytochemical, physicochemical characterisation and in vitro dissolution profile
Ciências agrárias e biológicas · Journal of Thermal Analysis and Calorimetry
Role of alpha-terpineol modulating pathway nitric oxide into coronary tissues: A confluent mechanism for the cardioprotection?
Medicina · Tissue and Cell
Broad-spectrum antiviral activity of benzothiazole-acrylamide hybrids against Zika, Dengue, Chikungunya, and Sindbis viruses
Medicina · Results in Chemistry

2025 5

Assessment of MepA inhibition potential using thiadiazine derivatives through fluorometry, docking, and qPCR
Medicina · Gene Reports
Evaluation of the Efflux Pump Inhibition Activity of Thiadiazine-Derived Compounds Against the Staphylococcus aureus 1199B Strain
Medicina · Pharmaceuticals
In vitro Antitumor Activity and Electrochemical Studies of Bio-Electroactive Anthraquinone Derivatives in Glioblastoma
Farmacologia e toxicologia · Anais da Academia Brasileira de Ciências
Alpha-synuclein aggregation in Parkinson’s disease
Medicina · Advances in protein chemistry and structural biology
Antidiabetic Activity and Inhibitory Effects of Derivatives of Advanced Aminoguanidine Glycation
Bioquímica, genética e biologia molecular · ACS Omega

2024 8

Insights from Syzygium aromaticum Essential Oil: Encapsulation, Characterization, and Antioxidant Activity
Ciências agrárias e biológicas · Pharmaceuticals
Thiazine-derived compounds in inhibiting efflux pump in Staphylococcus aureus K2068, mepA gene expression, and membrane permeability alteration
Medicina · Biomedicine & Pharmacotherapy
Nanomolar activity of coumarin-3-thiosemicarbazones targeting Trypanosoma cruzi cruzain and the T. brucei cathepsin L-like protease
Medicina · European Journal of Medicinal Chemistry
A consensus reverse docking approach for identification of a competitive inhibitor of acetyltransferase enhanced intracellular survival protein from Mycobacterium tuberculosis
Farmacologia e toxicologia · Bioorganic & Medicinal Chemistry
Assessment In vitro and In silico of the Activity of Thiadiazines as NorA Efflux Pump Inhibitors
Medicina · Current Microbiology
Evaluating efflux pump inhibition in Staphylococcus aureus 1199B strain using thiadiazine-derived compounds: In vitro and in silico approaches
Medicina · Biochimie
Larvicidal activity of diterpenes from Xylopia langsdorfiana St. Hilaire & Tulasne (Annonaceae) against Aedes aegypti linn. (diptera: culicidae)
Ciências agrárias e biológicas · Natural Product Research
Development of Syzygium aromaticum (L.) essential oil encapsulates by ionic gelification and evaluation of antioxidant activity
Ciências agrárias e biológicas · Concilium

2023 2

Design, synthesis, antiviral evaluation, and In silico studies of acrylamides targeting nsP2 from Chikungunya virus
Medicina · European Journal of Medicinal Chemistry
PI3K Signaling Pathways as a Molecular Target for Glioblastoma Multiforme
Medicina · Current Protein and Peptide Science

2022 8

Advances in Computational Methods to Discover New NS2B-NS3 Inhibitors Useful Against Dengue and Zika Viruses
Farmacologia e toxicologia · Current Topics in Medicinal Chemistry
Development of a Polymeric Membrane Impregnated with Poly-Lactic Acid (PLA) Nanoparticles Loaded with Red Propolis (RP)
Ciências agrárias e biológicas · Molecules
Strategies in Medicinal Chemistry to Discover New Hit Compounds against Ebola Virus: Challenges and Perspectives in Drug Discovery
Medicina · Mini-Reviews in Medicinal Chemistry
Fragment-based design of α-cyanoacrylates and α-cyanoacrylamides targeting Dengue and Zika NS2B/NS3 proteases
Farmacologia e toxicologia · New Journal of Chemistry
Bradykinin-target therapies in SARS-CoV-2 infection: current evidence and perspectives
Medicina · Naunyn-Schmiedeberg s Archives of Pharmacology
In vitro antitumor activity of dialkylamine-1,4-naphthoquinones toward human glioblastoma multiforme cells
Farmacologia e toxicologia · New Journal of Chemistry
LQM10, a guanylhydrazone derivative, reduces nociceptive and inflammatory responses in mice
Medicina · Fundamental and Clinical Pharmacology
Inhibitors Targeting Hepatitis C Virus (HCV) Entry
Medicina · Mini-Reviews in Medicinal Chemistry

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